MR Spectroscopy: AI methods for quantification
Unsupervised deep learning methods for frequency and phase correction (FPC)We developed two unsupervised deep learning methods for FPC: a cr…
Read more →Research Areas
MR Spectroscopy: Development coordination and co-development of jMRUI
jMRUI is a software suite for exploration and advanced time-domain analysis of magnetic resonance spectroscopy (MRS) and spectroscopic imagi…
Read more →
Perfusion MRI: AI methods for DCE-(DSC-)MRI
Quantitative analysis of perfusion MRI traditionally relies on model fitting, which is often computationally demanding and ill-posed, leadin…
Read more →
Perfusion MRI: Blind-deconvolution AIF estimation
The accuracy of perfusion-parameter estimation in DCE- and DSC-MRI perfusion imaging depends primarily on the Arterial Input Function (AIF),…
Read more →
Perfusion MRI: Development of PerfLab
We have been developing online software for perfusion analysis, PerfLab. It provides standard perfusion analysis methods of DCE-MRI data and…
Read more →
Perfusion MRI: Quantification of blood-brain-barrier permeability
Our research focuses on developing and validating advanced MRI-based methods for quantifying blood–brain barrier (BBB) permeability with hig…
Read more →
Perfusion MRI: Self-gated cardiac FAIR-ASL
Based on our self-gated T1 quantification method [1], we derived a method for quantifying myocardial perfusion. The method uses the principl…
Read more →
Perfusion MRI: Simultaneous DCE-DSC-MRI
Simultanous acquisition and quantification of DCE-MRI and DSC-MRIA combination of DCE- and DSC-MRI may be a way to enhance the diagnostic va…
Read more →
Perfusion MRI: Spatially regularized estimation of perfusion maps
We have been developing new methods for DCE-MRI perfusion analysis that take the spatial context into account to improve the accuracy of per…
Read more →
T1 relaxometry: self-gated quantification in the rat’s myocardium
Imaging myocardium is difficult let alone obtaining quantitative parameters. We developed fast self-gated acquisition based on inversion rec…
Read more →Projects
Support for "Proof-of-Concept" activities at the Institute of Scientific Instruments of the CAS, v. v. i.
–
The goal of the presented project is, in addition to expansion of the existing system of transfer of new R&D knowledge, strengthening resear…
Read more →
PerfLab
–
The main goal of this project is to make PerfLab accessible to a broader professional community, subject it to testing and validation, and s…
Read more →
Modernization of Czech-BioImaging research infrastructure
–
The aim of the project is effective, coordinated and transparent quality assurance and further development of services provided by the Czech…
Read more →
National Infrastructure for Biological and Medical Imaging
–
The aim of Czech-BioImaging is to continue to develop a harmonized national network that coordinates the development of biomedical imaging,…
Read more →
Biodistribution and real-time monitoring of free or apoferritin-encapsulated charged cholinesterase reactivators
–
Oxime cholinesterase reactivators are used for life endangering intoxications caused by organophosphate agents. However, clinically used (so…
Read more →
Multi-Contrast Quantification of Perfusion Using Joint Magnetic Resonance Contrast-Enhanced and Arterial-Spin-Labeling Approaches
–
Magnetic resonance (MR) perfusion imaging is used for diagnostics and therapy monitoring mostly in oncology, neurology and cardiology, provi…
Read more →