Opening Mouse BloodâBrain Barrier and Thermal Manipulation with FUS in UHF-MR System
An advanced training workshop hosted by our facility.
This hands-on course introduces MR-compatible focused ultrasound (FUS) for opening the bloodâbrain barrier (BBB) and its assessment using MR perfusion imaging. Participants will explore the complete workflow, from FUS system setup and thermal manipulation to MRI acquisition and offline data processing in PerfLab.
Programme
Theoretical part
Focused ultrasound, MR-compatible FUS hardware and BBB opening
Microbubbles, cavitation and thermal manipulation
MR perfusion imaging and BBB permeability assessment
Animal preparation and experimental workflow
Introduction to the PerfLab software
Practical part
FUS system and phantom setup
Microbubble and contrast-agent demonstrations
MRI acquisition workflow
Demonstration of mouse experimental workflow
Offline MRI data processing and BBB opening analysis in PerfLab
Practical information
Date: December 7, 2026, from 9:00
Location: Institute of Scientific Instruments of the CAS, Brno
On-site: maximum 10 participants
Online: capacity unlimited
Registration & detailed programme here
Contact: OndĆej MacĂÄek · macicek@isibrno.cz